Western inferno provokes a lot of finger-pointing, but little action

Spending a little to save a lot

Phase III studies of disease-modifying agents for neurodegenerative disorders generally require hun­ dreds of patients to be followed for at least 2 years at a cost of millions of dollars. No matter how promis­ ing an agent may appear in preclinical studies and animal models, preliminary evidence that the treat­ ment is likely to be helpful in patients (proof-of­ concept) and that it is reasona...

Give a little ... get a lot.

Circumferential little finger nailplate

A Thoma, I Alexopoulou. Circumferential little finger nailplate. Can J Plast Surg 1995;3(3):161-162. This is a case report of a seven-year-old female who presented with a congenital anomaly of the little finger in which the nailplate was circumferentially covering the tip of the distal phalanx. There was a well-developed eponychial fold on the palmar aspect of the digit. This rare congenital `c...

A little bit of lithium does a lot for hydrogen.

From detailed assessments of electronic structure, we find that a combination of significantly quantal elements, six of seven atoms being hydrogen, becomes a stable metal at a pressure approximately 1/4 of that required to metalize pure hydrogen itself. The system, LiH(6) (and other LiH(n)), may well have extensions beyond the constituent lithium. These hypothetical materials demonstrate that n...

A Lot of Flavor Physics from a Little Symmetry

Recent neutrino parameter measurements place increasingly stringent constraints on acceptable supersymmetric theories of flavor. A very fruitful approach is the application of non-Abelian discrete gauged flavor symmetries Gf . We discuss a highly successful model using Gf = T ′ × Z3, where T ′ is a non-Abelian group based on the symmetries of a tetrahedron. This model reproduces the basic featu...